Leonard Girnita : rechercher sur Z-Library

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1

The tale of a tail: The secret behind IGF-1Râs oncogenic power

Crudden, Caitrin, Girnita, Leonard

Journal:

Science Signaling

Année:

2020

Fichier:

PDF, 241 KB

2020

2

A link between basic fibroblast growth factor (bFGF) and EWS/FLI-1 in Ewing's sarcoma cells

Girnita, Leonard, Girnita, Ada, Wang, Min, Meis-Kindblom, Jeanne M, Kindblom, Lars-Gunnar, Larsson, Olle

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 152 KB

english, 2000

3

Gene expression profile by blocking the SYT-SSX fusion gene in synovial sarcoma cells. Identification of XRCC4 as a putative SYT-SSX target gene

Xie, Yuntao, Törnkvist, Maria, Aalto, Yan, Nilsson, Gunnar, Girnita, Leonard, Nagy, Bálint, Knuutila, Sakari, Larsson, Olle

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 138 KB

english, 2003

4

The cyclolignan PPP induces activation loop-specific inhibition of tyrosine phosphorylation of the insulin-like growth factor-1 receptor. Link to the phosphatidyl inositol-3 kinase/Akt apoptotic pathway

Vasilcanu, Daiana, Girnita, Ada, Girnita, Leonard, Vasilcanu, Radu, Axelson, Magnus, Larsson, Olle

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 377 KB

english, 2004

5

Blocking IGF-1R phosphorylation attenuates intimal hyperplasia through effects on SMC apoptosis, adhesion, migration and proliferation

Joy Roy, Anton Razuvaev, Magnus Axelsson, Leonard Girnita, Olle Larsson, Ulf Hedin

Journal:

Vascular Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 55 KB

english, 2006

6

Aberrant intracellular IGF-1R β-subunit makes receptor knockout cells (IGF1R-/-) susceptible to oncogenic transformation

Natalia Natalishvili, Magnus Axelson, Leonard Girnita, Olle Larsson, Daiana Vasilcanu

Journal:

Experimental Cell Research

Année:

2009

Langue:

english

Fichier:

PDF, 986 KB

english, 2009

7

Inhibition of VEGF secretion and experimental choroidal neovascularization by picropodophyllin (PPP), an inhibitor of the insulin-like growth factor-1 receptor

Mario A. Economou, Jiangmei Wu, Daiana Vasilcanu, Linda Rosengren, Charlotta All-Ericsson, Ingeborg Van Der Ploeg, Eline Menu, Leonard Girnita, Magnus Axelson, Olle Larsson, Stefan Seregard, Anders Kv

Journal:

Acta Ophthalmologica (Blackwell)

Année:

2008

Langue:

english

Fichier:

PDF, 490 KB

english, 2008

8

The insulin-like growth factor-I receptor inhibitor picropodophyllin causes tumor regression and attenuates mechanisms involved in invasion of uveal melanoma cells

Ada Girnita, Charlotta All-Ericsson, Mario A. Economou, Kristina Åström, Magnus Axelson, Stefan Seregard, Olle Larsson, Leonard Girnita

Journal:

Acta Ophthalmologica (Blackwell)

Année:

2008

Langue:

english

Fichier:

PDF, 822 KB

english, 2008

9

Receptors for the liver synthesized growth factors IGF-1 and HGF/SF in uveal melanoma: intercorrelation and prognostic implications

Mario A. Economou, Charlotta All-Ericsson, Vladimir Bykov, Leonard Girnita, Armando Bartolazzi, Olle Larsson, Stefan Seregard

Journal:

Acta Ophthalmologica (Blackwell)

Année:

2008

Langue:

english

Fichier:

PDF, 291 KB

english, 2008

10

Oral picropodophyllin (PPP) is well tolerated in vivo and inhibits IGF-1R expression and growth of uveal melanoma

Mario A. Economou, Sandra Andersson, Diana Vasilcanu, Charlotta All-Ericsson, Eline Menu, Ada Girnita, Leonard Girnita, Magnus Axelson, Stefan Seregard, Olle Larsson

Journal:

Acta Ophthalmologica (Blackwell)

Année:

2008

Langue:

english

Fichier:

PDF, 276 KB

english, 2008

11

Regulatory Role of Mevalonate and N-Linked Glycosylation in Proliferation and Expression of the EWS/FLI-1 Fusion Protein in Ewing's Sarcoma Cells

Min Wang, Yuntao Xie, Leonard Girnita, Gunnar Nilsson, Anica Dricu, Johan Wejde, Olle Larsson

Journal:

Experimental Cell Research

Année:

1999

Langue:

english

Fichier:

PDF, 241 KB

english, 1999

12

IGF-1R tyrosine kinase expression and dependency in clones of IGF-1R knockout cells (R−)

Linda Rosengren, Daiana Vasilcanu, Radu Vasilcanu, Sandra Fickenscher, Bita Sehat, Nathalia Natalishvili, Sean Naughton, Shucheng Yin, Ada Girnita, Leonard Girnita, Magnus Axelson, Olle Larsson

Journal:

Biochemical and Biophysical Research Communications

Année:

2006

Langue:

english

Fichier:

PDF, 186 KB

english, 2006

13

Differential roles of SS18–SSX fusion gene and insulin-like growth factor-1 receptor in synovial sarcoma cell growth

Maria Törnkvist, Natalia Natalishvili, Yuntao Xie, Ada Girnita, Pádraig D’Arcy, Bertha Brodin, Magnus Axelson, Leonard Girnita

Journal:

Biochemical and Biophysical Research Communications

Année:

2008

Langue:

english

Fichier:

PDF, 866 KB

english, 2008

14

Insulin/insulin-like growth factor (IGF) stimulation abrogates an association between a deubiquitinating enzyme USP7 and insulin receptor substrates (IRSs) followed by proteasomal degradation of IRSs

Hidehito Yoshihara, Toshiaki Fukushima, Fumihiko Hakuno, Yasushi Saeki, Keiji Tanaka, Akihiro Ito, Minoru Yoshida, Shun-ichiro Iemura, Tohru Natsume, Tomoichiro Asano, Kazuhiro Chida, Leonard Girnita,

Journal:

Biochemical and Biophysical Research Communications

Année:

2012

Langue:

english

Fichier:

PDF, 471 KB

english, 2012

15

Possible use of flavonoids as cell growth inhibitors in malignant melanoma

Ada Girnita, Leonard Girnita, Magnus Axelson, Olle Larsson

Journal:

Journal of the American Academy of Dermatology

Année:

2004

Langue:

english

Fichier:

PDF, 47 KB

english, 2004

16

Tamoxifen-induced cell death in malignant melanoma cells: possible involvement of the insulin-like growth factor-1 (IGF-1) pathway

Lena Kanter-Lewensohn, Leonard Girnita, Ada Girnita, Anica Dricu, Gunilla Olsson, Louise Leech, Gunnar Nilsson, Agneta Hilding, Johan Wejde, Kerstin Brismar, Olle Larsson

Journal:

Molecular and Cellular Endocrinology

Année:

2000

Langue:

english

Fichier:

PDF, 232 KB

english, 2000

17

P-19 DUAL FUNCTION FOR MDM 2 MEDIATED UBIQUITINATION OF IGF-1R: DOWNREGULATION AND SIGNAL ACTIVATION

Leonard Girnita, Ada Girnita, Olle Larsson

Journal:

Growth Hormone & IGF Research

Année:

2006

Langue:

english

Fichier:

PDF, 53 KB

english, 2006

18

P-50 ESTROGEN RECEPTOR AND IGF-1R IN BREAST CANCER CELLS: WHAT IS THE RELATIONSHIP?

Ada Girnita, Leonard Girnita, Magnus Axelson, Olle Larsson

Journal:

Growth Hormone & IGF Research

Année:

2006

Langue:

english

Fichier:

PDF, 46 KB

english, 2006

19

Malignant solitary fibrous tumour of the orbit

Leonard Girnita, Sven Sahlin, Abiel Orrego, Stefan Seregard

Journal:

Acta Ophthalmologica (Blackwell)

Année:

2009

Langue:

english

Fichier:

PDF, 575 KB

english, 2009

20

Something old, something new and something borrowed: emerging paradigm of insulin-like growth factor type 1 receptor (IGF-1R) signaling regulation

Girnita, Leonard, Worrall, Claire, Takahashi, Shin-Ichiro, Seregard, Stefan, Girnita, Ada

Journal:

Cellular and Molecular Life Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2014

21

The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling

Razuvaev, Anton, Henderson, Bimma, Girnita, Leonard, Larsson, Olle, Axelson, Magnus, Hedin, Ulf, Roy, Joy

Journal:

Journal of Vascular Surgery

Année:

2007

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2007

22

New Picropodophyllin Analogs via Palladium-Catalyzed Allylic Alkylation−Hiyama Cross-Coupling Sequences

Vitale, Maxime, Prestat, Guillaume, Lopes, David, Madec, David, Kammerer, Claire, Poli, Giovanni, Girnita, Leonard

Journal:

Journal of Organic Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 394 KB

english, 2008

23

Expression of Insulin-Like Growth Factor-1 Receptor (IGF-1R) and p27 Kip1 in Melanocyte Tumors: A Potential Regulatory Role of IGF-1 Pathway in Distribution of p27 Kip1 between Different Cyclins

Kanter-Lewensohn, Lena, Dricu, Anica, Girnita, Leonard, Wejde, Johan, Larsson, Olle

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 871 KB

english, 2000

24

Repeatable, Inducible Micro-RNA-Based Technology Tightly Controls Liver Transgene Expression

Oprea, Iulian I, Viola, Joana R, Moreno, Pedro M D, Simonson, Oscar E, Rodin, Sergey, Teller, Nathalie, Tryggvason, Karl, Lundin, Karin E, Girnita, Leonard, Smith, Carl Inge Edvard

Journal:

Molecular Therapy — Nucleic Acids

Année:

2014

Langue:

english

Fichier:

PDF, 721 KB

english, 2014

25

The dichotomy of the Insulin-like growth factor 1 receptor: RTK and GPCR: friend or foe for cancer treatment?

Crudden, Caitrin, Ilic, Marina, Suleymanova, Naida, Worrall, Claire, Girnita, Ada, Girnita, Leonard

Journal:

Growth Hormone & IGF Research

Année:

2015

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2015

26

Receptors for the Liver Synthesized Growth Factors IGF-1 and HGF/SF in Uveal Melanoma: Intercorrelation and Prognostic Implications

Economou, Mario A., All-Ericsson, Charlotta, Bykov, Vladimir, Girnita, Leonard, Bartolazzi, Armando, Larsson, Olle, Seregard, Stefan

Journal:

Investigative Ophthalmology & Visual Science

Année:

2005

Langue:

english

Fichier:

PDF, 299 KB

english, 2005

27

Targeting the IGF-1R: The Tale of the Tortoise and the Hare

Crudden, Caitrin, Girnita, Ada, Girnita, Leonard

Journal:

Frontiers in Endocrinology

Année:

2015

Langue:

english

Fichier:

PDF, 3.76 MB

english, 2015

28

Non-coding RNAs: the cancer genome dark matter that matters!

Ling, Hui, Girnita, Leonard, Buda, Octavian, Calin, George A.

Journal:

Clinical Chemistry and Laboratory Medicine

Année:

2017

Langue:

english

Fichier:

PDF, 1.20 MB

english, 2017

29

Genome-Wide Screen for MicroRNAs Reveals a Role for miR-203 in Melanoma Metastasis

Lohcharoenkal, Warangkana, Das Mahapatra, Kunal, Pasquali, Lorenzo, Crudden, Caitrin, Kular, Lara, Akkaya Ulum, Yeliz Z., Zhang, Lingyun, Xu Landén, Ning, Girnita, Leonard, Jagodic, Maja, Ståhle, Mona

Journal:

The Journal of Investigative Dermatology

Année:

2017

Langue:

english

Fichier:

PDF, 4.86 MB

english, 2017

30

Diseases in the Aging Society Caused by Modulation of Insulin-Like Activities

TAKAHASHI, Shin-Ichiro, HAKUNO, Fumihiko, KAMEI, Hiroyasu, Girnita, Leonard, Torres-Aleman, Ignacio, HIGASHI, Yusuke, FUKUSHIMA, Toshiaki, SHIBANO, Takashi, OZOE, Atsufumi, YAMANAKA, Daisuke

Journal:

KAGAKU TO SEIBUTSU

Année:

2013

Fichier:

PDF, 1.60 MB

2013

31

Role of Ubiquitination in IGF-1 Receptor Signaling and Degradation

Sehat, Bita, Andersson, Sandra, Vasilcanu, Radu, Girnita, Leonard, Larsson, Olle, Blagosklonny, Mikhail

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 705 KB

english, 2007

32

Oral Picropodophyllin (PPP) Is Well Tolerated In Vivo and Inhibits IGF-1R Expression and Growth of Uveal Melanoma

Economou, Mario A., Andersson, Sandra, Vasilcanu, Diana, All-Ericsson, Charlotta, Menu, Eline, Girnita, Ada, Girnita, Leonard, Axelson, Magnus, Seregard, Stefan, Larsson, Olle

Journal:

Investigative Ophthalmology & Visual Science

Année:

2008

Langue:

english

Fichier:

PDF, 220 KB

english, 2008

33

Inhibition of VEGF Secretion and Experimental Choroidal Neovascularization by Picropodophyllin (PPP), an Inhibitor of the Insulin-like Growth Factor-1 Receptor

Economou, Mario A., Wu, Jiangmei, Vasilcanu, Daiana, Rosengren, Linda, All-Ericsson, Charlotta, van der Ploeg, Ingeborg, Menu, Eline, Girnita, Leonard, Axelson, Magnus, Larsson, Olle, Seregard, Stefan

Journal:

Investigative Ophthalmology & Visual Science

Année:

2008

Langue:

english

Fichier:

PDF, 529 KB

english, 2008

34

Ruthenium-106 versus iodine-125 plaque brachytherapy of 571 choroidal melanomas with a thickness of ≥5.5 mm

Filì, Maria, Trocme, Eric, Bergman, Louise, See, Thonnie Rose Ong, André, Helder, Bartuma, Katarina, Girnita, Leonard, All-Eriksson, Charlotta, Seregard, Stefan, Stålhammar, Gustav

Journal:

British Journal of Ophthalmology

Année:

2019

Langue:

english

Fichier:

PDF, 993 KB

english, 2019

35

c-Kit–Dependent Growth of Uveal Melanoma Cells: A Potential Therapeutic Target?

All-Ericsson, Charlotta, Girnita, Leonard, Mu¨ller-Brunotte, Anja, Brodin, Bertha, Seregard, Stefan, O¨stman, Arne, Larsson, Olle

Journal:

Investigative Ophthalmology & Visual Science

Année:

2004

Langue:

english

Fichier:

PDF, 473 KB

english, 2004

36

Decrypting noncoding RNA interactions, structures, and functional networks

Fabbri, Muller, Girnita, Leonard, Varani, Gabriele, Calin, George A.

Journal:

Genome Research

Année:

2019

Langue:

english

Fichier:

PDF, 3.56 MB

english, 2019

37

Non-Coding RNAs in IGF-1R Signaling Regulation: The Underlying Pathophysiological Link between Diabetes and Cancer

Chen, Baoqing, Li, Junyan, Chi, Dongmei, Sahnoune, Iman, Calin, Steliana, Girnita, Leonard, Calin, George A.

Journal:

Année:

2019

Fichier:

PDF, 1.53 MB

2019

38

Editor's Note: Estrogen Receptor Î± Promotes Breast Cancer by Reprogramming Choline Metabolism

Jia, Min, Andreassen, Trygve, Jensen, Lasse, Bathen, Tone Frost, Sinha, Indranil, Gao, Hui, Zhao, Chunyan, Haldosen, Lars-Arne, Cao, Yihai, Girnita, Leonard, Moestue, Siver Andreas, Dahlman-Wright, Ka

Journal:

Cancer Research

Année:

2019

Fichier:

PDF, 159 KB

2019